Evaluation of antidepressant effects of rosuvastatin in male albino mice by forced swim test model

Objective: To evaluate the antidepressant activity of Rosuvastatin in male albino mice. Method: Thirty male swiss albino mice were selected for forced swim test model. There were five groups and each group had six animals. The control group received Normal saline (10ml/kg I.P), the standard Imipramine (10mg/kg I.P), the 3 test group received Rosuvastatin (10mg/kg, 15mg/kg, 20mg/kg I.P) respectively. The test was conducted 30mins after injecting the drugs by forced swim test model. Duration of immobility was noted. Statistical analysis was performed using Mean +/- SEM. One way ANOVA followed by Tukey’s post hoc test was done P