Features of EEG in patients with disorders due to psychoactive substance use during olfactory stimulation

Electroencephalographic (EEG) spectra have been analyzed under baseline conditions and during olfactory stimulation in substance-dependent and healthy subjects. The intergroup differences in the EEG spectra resulting from an increase in the power of cortical bioelectric potentials in patients with disorders due to psychoactive substance use were recorded in the parietal and temporal EEG leads. Interhemispheric differences have been found in the contribution of different frequencies to the spectral characteristics of the EEG. In patients with addictive disorders, in the temporal area of the left hemisphere, in the high-frequency range, a significant increase in the power of bioelectric potentials was recorded under baseline conditions and during olfactory stimulation. An increased power of α activity was typical of the temporal area of the right hemisphere in patients with disorders due to psychoactive substance use compared to the healthy subjects. The neurophysiological patterns found may be related to the psychological and behavioral features of addictive disorders.