Organocatalytic Synthesis and Evaluation of 7-Chloroquinoline-1,2,3-triazoyl Carboxamides as Potential Antinociceptive, Anti-inflammatory and Anticonvulsant Agent.

Ethel A. Wilhelm,Niége C. Machado,Andrieli B. Pedroso,Bruna Goldani,Natália Seus,Sidnei Moura,Lucielli Savegnago,Raquel G. Jacob,Diego Alves

Organocatalytic Synthesis and Evaluation of 7-Chloroquinoline-1,2,3-triazoyl Carboxamides as Potential Antinociceptive, Anti-inflammatory and Anticonvulsant Agent.

2015

Ethel A. Wilhelm
Niége C. Machado
Andrieli B. Pedroso
Bruna Goldani
Natália Seus
Sidnei Moura
Lucielli Savegnago
Raquel G. Jacob
Diego Alves

Derivative (IIIa) shows an effect on central pain modulation by presenting antinociceptive and antiinflammatory characteristics for combating acute pain.

Keywords:

Central pain
Nociception
Anti-inflammatory
Anticonvulsant Agent
Pharmacology
Organocatalysis
Chemistry
Organic chemistry
acute pain
triazole derivatives

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