Withanolides from Physalis peruviana

Two new withanolides isolated from the whole plant material of Physalis peruviana (Solanaceae) have been characterized as (20R,22R)-5α,6β,14α,20,27-pentahydroxy-1-oxowith-24-enolide, and (20S,22R)-5β,6β-epoxy-4β,14β,15α-trihydroxy-1-oxowith-2,24-dienolide in addition to the known withanolides, withaphysanolide and viscosalactone B on the basis of spectroscopic techniques and chemical transformations.