The Use of Bifonazole in the First 2 Years of Life

We have studied the activity of bifonazole in patients in the first 2 years of life suffering from napkin dermatitis in which Candida was verified by culture tests. The patients were chosen from children recovered in the departments of Pediatric “Bambino Gesu” Hospital Clinic and from the Outpatients Department. In five hospitalized patients the following parameters were checked before the treatment and after 3 weeks of therapy: hemochromecytometric test, glycemia, azotemia, creatininemia, bilirubinemia, GOT, GPT, LDH, ALP, ALS; the parameters did not show any change between the checks. Every patient underwent a topical treatment with bifonazole 1% cream for 3 weeks: the results were very good with only a few patients having slight redness at the end of therapy, which disappeared without any further treatment.