Transfer and metabolism of norepinephrine studied from maternal-to-fetal and fetal-to-maternal sides in the in vitro perfused human placental lobe

Abstract An in vitro system for the dual perfusion of an isolated lobe of human placenta was used to study transfer and metabolism of 3 H-labeled norepinephrine at two different concentrations. At 39 μmol/L, the transfer of total radioactivity from the maternal to the fetal side was 11.60% ± 0.60% and significantly higher (p