A novel human Fc-optimized ICAM-1/CD54 antibody (MSH-TP15e) with potent anti-myeloma activity in vitro and in vivo

Figure 1 WT PRL-3 overexpression increased phosphorylation of Src-Y416 in human myeloma cell line INA-6. Cells are depleted of IL-6 for 3 hours before incubation without or with 1 or 0.01 ng/mL of IL-6 for overnight