VRK3-mediated nuclear localization of HSP70 prevents glutamate excitotoxicity-induced apoptosis and Aβ accumulation via enhancement of ERK phosphatase VHR activity.

Haengjin Song,Wanil Kim,Sung Hoon-Kim,Kyong-Tai Kim

VRK3-mediated nuclear localization of HSP70 prevents glutamate excitotoxicity-induced apoptosis and Aβ accumulation via enhancement of ERK phosphatase VHR activity.

2016

Haengjin Song
Wanil Kim
Sung Hoon-Kim
Kyong-Tai Kim

VRK3-mediated nuclear localization of HSP70 prevents glutamate excitotoxicity-induced apoptosis and Aβ accumulation via enhancement of ERK phosphatase VHR activity

Keywords:

Cell biology
Apoptosis
MAPK/ERK pathway
Excitotoxicity
Dual Specificity Phosphatase 3
Glutamate receptor
Biochemistry
Glutamic acid
Chemistry
Nuclear localization sequence
Phosphatase
Kinase
Downregulation and upregulation
Cell nucleus

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