Small interfering RNA for specific inhibition of MAGEA1 gene expression and application thereof

The invention provides small interfering RNA for specific inhibition of MAGEA1 gene expression and the application thereof. The positive-sense strand sequence and the antisense strand sequence of the small interfering RNA are shown in SEQ ID NO.1-2. The MAGEA1 target sequence interfered by the small interfering RNA is shown in SEQ ID NO.3. The small interfering RNA inhibits MAGEA1 gene expression by acting on the MAGEA1 target sequence, can be used for preparing drugs for adjusting expression of MAGEA1 genes in cells or organisms, can also be used for preparing drugs for treating tumor especially melanoma, and has broad application prospects.