Plasma Cell-Free DNA Testing of Patients With EGFR Mutant Non–Small-Cell Lung Cancer: Droplet Digital PCR Versus Next-Generation Sequencing Compared With Tissue-Based Results

Christi M J Steendam,Peggy N. Atmodimedjo,Evert de Jonge,Marthe S. Paats,Cor van der Leest,Esther Oomen-de Hoop,Maurice P.H.M. Jansen,Marzia Del Re,Jan H. von der Thüsen,Winand N. M. Dinjens,Ron H.N. van Schaik,Joachim Aerts,Hendrikus J. Dubbink

Plasma Cell-Free DNA Testing of Patients With EGFR Mutant Non–Small-Cell Lung Cancer: Droplet Digital PCR Versus Next-Generation Sequencing Compared With Tissue-Based Results

2019

Christi M J Steendam
Peggy N. Atmodimedjo
Evert de Jonge
Marthe S. Paats
Cor van der Leest
Esther Oomen-de Hoop
Maurice P.H.M. Jansen
Marzia Del Re
Jan H. von der Thüsen
Winand N. M. Dinjens
Ron H.N. van Schaik
Joachim Aerts
Hendrikus J. Dubbink

PURPOSETo compare the results of plasma cell-free DNA (cfDNA) droplet digital PCR (ddPCR) and next-generation sequencing (NGS) on detection of epidermal growth factor receptor (EGFR) primary activa...

Keywords:

Epidermal growth factor receptor
DNA
Cell
Plasma cell
Molecular biology
Mutant
Digital polymerase chain reaction
DNA sequencing
Chemistry
Lung cancer
free dna

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