HISTOPATHOLOGICAL SPECTRUM OF CNS TUMOURS IN A TERTIARY CARE REFERRAL CENTRE - A ONE YEAR STUDY

A retrospective study was carried out on biopsy specimens received in Department Of Pathology, PGIMS, Rohtak, for one year. A total of 77 biopsy specimens sent by Neurosurgery Department of the institute during the year were reviewed. The specimens were processed by routine techniques and immunohistochemistry performed wherever necessary. Majority of CNS tumors were malignant with male: female ratio of 1.6: 1 mostly in the age group of 36-50 years. Most neoplasms were found to occur in the anterior fossa than posterior fossa, anterior fossa accounting for 71.42% of the total cases studied. Astrocytictumours constituted the largest category with 43 cases accounting for 55.84% of CNS tumours out of which majority were grade II at the time of diagnosis. Astrocytomas constitute the largest group of primary CNS tumors. In our study, we found that astrocytic tumours are the most prevalent tumours and diffuse infiltrating astrocytomas i.e. grade II is the most common group of astrocytoma in adults.