Β-crystalline form of naputinib tosylate, preparation method therefor and pharmaceutical composition containing same

The present invention providesβ-crystalline form of 2 crystalline hydrate of compound N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(ethoxy)-6-quinazolinyl]-4-(dimethylamino)-2-crotonamide tosylate, which has stable form and definite melting point, good chemical stability, resistance to high temperature and light, and is suitable for pharmaceutical use.