Pharmacologic Treatment of Bronchiolitis in Infants and Children

Results: Of 797 abstracts identified in the literature search, we included 54 randomized controlled trials. This review includes 44 studies of the most common interventions: epinephrine (n=8), 2-agonist bronchodilators (n=13), corticosteroids (n=13), and ribavirin (n=10). Studies were, in general, underpowered to detect statistically significant outcome differences between study groups. Few studies collected data on outcomes that are of great importance to parents and clinicians, such as the need for and duration of hospitalization.