Acute toxicity’s survey of the MISCA-MATÈS soap

We studied the cutaneous MISCA-MATES toxicity soap humans. The test of irritation at the man is indispensable to specify the potential irritating power of some better cosmetic preparations. Thirty soaps of MISCA-MATES experimentation were delayed on thirty voluntary people. Two methods have been used. The first consists in applying a quantity of soap foam on the hand of the volunteers during 24 hours. The test has been repeated at the same place during 7 days except if an erythema develops in which case the test is stopped. The treatment has not been interrupted after the 7 days of experimentation. The second method consists in distributing to each volunteer a soap for the bath during 7 days and we noted the effects which could produce the soap on their respective skins. The analysis shows that one person out of thirty (3.33 %) felt a slight burn when applying soap while twenty nine persons (96.67 %) felt no burn.