Bone destruction by receptor activator of nuclear factor κB ligand-expressing T cells in chronic gouty arthritis.
2011
Introduction
The purpose of this study was to analyze the cellular expressions of pro-resorptive cytokines in gouty tophus tissues, to determine the capacity of monosodium urate monohydrate (MSU) crystals to induce these cytokines, and to understand the mechanisms of bone destruction in chronic gout.
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