GW27-e0569 Platelet Reactivity In Acute Coronary Syndrome according to CYP2C19 Phenotypes

Dual antiplatelet therapy (DAPT) with aspirin and clopidogrel was treatment for ACS or for patients undergoing PCI. Clopidogrel is a pro-drug that must be metabolized by the cytochrome P (CYP) 450 enzyme system to generate active metabolites. Metabolic activation by CYP2C19 is crucial for generation