Syntheses of 1-(2-bromo-3-hydroxypropyl)-and 1-(2-bromo-2-propenyl)isatins and theirβ-thiosemicarbazones

Only the bromine atom at the primary carbon atom participates in nucleophilic replacement by a trifluoroacetate ion and elimination of HBr in 1-(2,3-dibromopropyl)isatin.