Bacteriocin genes among E. coli strains: the incidence dependson genotype and phenotype of E. coli strains
2011
E. coli strains (n = 1670) isolated during years 2007-2010 in
the Czech Republic were collected from patients attending
regional hospitals in Brno. All strains were tested using
commercially available biochemical tests (ENTEROtest 16; Erba
Lachema, Ltd., Brno, Czech Republic) for their biochemical
activities, and with PCR for the presence to one out of four E.
coli phylogroups including group A, B1, B2, and D. Moreover,
the incidence of 29 bacteriocin-encoding determinants (i.e.
colicin and microcin encoding genes) was tested in each
individual E. coli strain. According to their biochemical
activity, 1670 E. coli strains clustered into 6 groups
containing 709, 50, 47, 744, 103, and 17 strains, respectively.
The two largest clusters differed in the incidence of both
phylogroups B2 and D and also in the incidence of bacteriocin
determinants of mH47, mM, E1 and K. In addition, the incidence
of colicinogenic strains was higher in the phylogroup A and B1
(p < 0.001) compared to combined B2 and D phylogroup strains.
Strains of phylogroup B2 most frequently encoded microcin H47
and strains of phylogroup D microcin B17 and colicin Js. The
incidence of individual bacteriocin encoding determinants is
therefore predominantly associated with particular E. coli
phylogroups and also with E. coli strains of specific
biochemical activity.
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