How to use the inactivated Japanese encephalitis virus particles as an adjuvant

Inactivated Japanese encephalitis virus particles to provide a method of using as an adjuvant. Japanese encephalitis virus (JEV) Beijing -1 strain was inoculated into Vero cells, the JEV-infected cells were purified from culture cells or culture supernatant JEV particles obtained by culturing, by inactivating the JEV particles with formalin how to use the inactivated JEV particles obtained as an adjuvant for various vaccines or a mixed vaccine, obtained by the production method and the production method of (mixed) vaccine comprising the step of containing the JEV particles (mixed) vaccine.