Rélations et Similarité Structurales: Régularité et Interactions Modèle Topologique Pulso a Environnement Variable

LFER correlations are justified by similarity functions developed in Taylor series. In the same formalism of Palm-Leffler-Wold, we present here an equation expressing similarity relations based on information extracted from a model with a variable environment (E) for a transition sO + s. This model is implemented in the PULSO topological method. Thanks to the procedure used, and called “nE/2s”, we can decompose the action of a substituent s in two terms related to the action of s on a reference environment EO and to its interaction on (E1 - EO). This model complements the usual one which has a constant environment E. The LFER relations, procedure (2E/ns) used especially for monosubstitutions, source of action parameters, is hardly efficient for Multiple Substitution Effect studies (MSE) because of the difficulties involved in evaluating interactions. Both models can be used either within the framework of a population (internal treatment) or with external references. The new model, alone or in association with the first, is used to identify the nature of the interactions to be associated with Taylor derivatives.