Reactions of K-Region Oxides of Carcinogenic and Noncarcinogenic Aromatic Hydrocarbons. Comparative Studies on Reactions with Nucleophiles and Acid-catalyzed Reactions

Several K-region arene oxides of carcinogenic and noncarcinogenic polycyclic aromatic hydrocarbons were synthesized, and their reactivities with various nucleophiles and their acid-catalyzed reactions were discussed. Relationship between these chemical reactivities and mutagenicity was also discussed.