Signaling path of the action of AVP on distal K + secretion

Signaling path of the action of AVP on distal K + secretion. Background. Previous studies from our laboratory have shown that luminal perfusion with arginine vasopressin (AVP) stimulates distal tubule secretory potassium flux (JK) via V1 re- ceptors (Am J Physiol 278:F809-F816, 2000). In the present work, we investigate the cell signaling mechanism of this process. Methods. In vivo stationary microperfusion was performed in rat cortical distal tubules and luminal K + was measured using