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Spotlight on the November 23 Issue

2021 
#### Notable in Neurology This Week This issue features a study that estimates the prevalence of patent foramen ovale in children with cryptogenic arterial ischemic stroke; another examines speech patterns in patients with Parkinson disease and how they change with dopaminergic therapy. A Review article describes how large-scale data-sharing and artificial intelligence can be used to monitor the progression and understand the mechanisms of multiple sclerosis using MRI. ### Association of CT-Based Hypoperfusion Index With Ischemic Core Enlargement in Patients With Medium and Large Vessel Stroke ![Graphic][1] Hypoperfusion index (HI) can estimate ischemic core growth rapidity. This study … [1]: /embed/inline-graphic-1.gif
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