The clinical significance of DIC were measured vWF, PLT and coagulation factor time

Objective Discusses the vWF content, the PLT quantity and the hemoglutination factor time change in the DIC early diagnosis clinical value. Methods The blood serum vWF determination uses the immunity turbidimetric method, uses Japan to produce the OLYMPUSAU-400 completely automatic biochemistry analyzer determination;PT, APIT, TT, the Fig determination uses the coagulation law, uses Japan to produce sysmex the CA-530 hemoglutination analyzer determination;The PLT counting prevents clotting the venous blood with EDTA-K2 , uses Japan to produce sysmex the K-1000 completely automatic blood corpuscle calculating instrument determination. Results DIC case group blood serum vWF and the Fig content, the PLT quantity and PT, APIT, the TT time obviously is higher than the normal control group, the difference had the significance significance(P ＜ 0. 01) , And elevates gradually along with the DIC development. Conclusion The vWF content,the PLT quantity and the hemoglutination factor time variation, may take the DIC early prediction,is important to diagnosis, moreover its dynamic determination result may also take monitors the DIC condition state of play, the appraisal curative effect, the judgment disease order of severity and the estimate prognosis important experiment parameter. Key words: DIC;  vWF;  PLT;  Coagulation factor time;  Clinical significance