Оценка эффективности вакцинации против пневмококковой инфекции у работников металлургического производства

The aim of this study was to evaluate efficacy of vaccination against pneumococcal infection using Pneumo23 vaccine in workers of metallurgical industry. Methods. The study involved workers of mining and metallurgical enterprises who exposed to occupational hazard factors regularly. The lung function was assessed using spyrometry. The severity of COPD was evaluated using the CAT questionnaire. Number and duration of day off periods due to respiratory diseases were also considered. All parameters were measured at baseline and in 12 and 24 months after vaccination. Results. The number of work off days due to respiratory diseases significant decreased in a year after vaccination with Pneumo 23 vaccine. Functional parameters and well-being improved and the impact of the disease on daily life decreased in 12 and 24 months after the vaccination. Conclusion. The results of the study confirmed the high efficacy and safety of vaccination with Pneumo 23 vaccine in workers of metallurgical enterprises.