Heterogeneous Catalytic Acylation of Benzo Crown Ether Using Acetic Anhydride

Abstract Benzo-15-crown-5 macrocycle has been acetylated using acetic anhydride and a series of cation exchanged clays. This acetylating method has great advantages such as the significant reduction of the formation of by-products, lower price and the possibility of environmental friendly process. Yields as high as 80% for the acetylated compound are reached in short times.