Synthesis of 4-(2′-substituted benzothiazoles)-5-mercapto-3-(substituted)-1,2,4-traizole derivatives for possible antimicrobiological activities.
2010
Benzothiazoles and traizoles have proven to be good antimicrobial agents certain 4-(2 ' substituted benzothiazoles)-5-mercapto-3-(substituted)-1,2,4-traizoles. The condensation of 2-Hydrazino benzothiazoles (Part-I) with potassium dithiocarbazinate suspension (Part-II), the result in compounds (A1A6) were prepared and have been characterized by melting point, TLC, UV, IR, 1 H-NMR spectral studies. All the compounds were evaluated for antibacterial and antifungal activities.
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