Long-term brain structural magnetic resonance imaging and cognitive functioning in children treated for acute lymphoblastic leukemia with high-dose methotrexate chemotherapy alone or combined with CNS radiotherapy at reduced total dose to 12 Gy

Olga Zajac-Spychala,Mikolaj Pawlak,Katarzyna Karmelita-Katulska,Jakub Pilarczyk,Katarzyna Derwich,Jacek Wachowiak

Long-term brain structural magnetic resonance imaging and cognitive functioning in children treated for acute lymphoblastic leukemia with high-dose methotrexate chemotherapy alone or combined with CNS radiotherapy at reduced total dose to 12 Gy

2017

Olga Zajac-Spychala
Mikolaj Pawlak
Katarzyna Karmelita-Katulska
Jakub Pilarczyk
Katarzyna Derwich
Jacek Wachowiak

Introduction The aim of this study was to assess the long-term side effects of central nervous system prophylaxis (high-dose chemotherapy alone vs chemotherapy and CNS radiotherapy) according to the ALL IC-BFM 2002.

Keywords:

Radiology
CNS Prophylaxis
Medicine
Methotrexate
Radiation therapy
Lymphoblastic Leukemia
Central nervous system
Magnetic resonance imaging
Chemotherapy
Neuroradiology
structural magnetic resonance imaging
Neurosurgery
Neurology

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