Idiopathic pulmonary fibrosis and lung cancer

Idiopathic pulmonary fibrosis-lung cancer (IPF-LC) occurs predominantly in the male, elderly and smokers.It is a potentially fatal disease with poor prognosis and without special clinical features and clear treatment strategies.Due to environmental and genetic factors, somatic gene mutation lead to diseases.Imaging simultaneously shows both pulmonary masses and honeycomb changes.At present, besides the pathogenesis is still unkown, the clinical features are lack of specificity and the prognosis is poor with a 6.9 month median survival.Therefore, clinicians should fully understand the possibility of the disease, strive for early diagnosis, optimize treatment stratigies and intervene comprehensively to improve survival and the quality of life in IPF-LC patients. Key words: Idiopathic pulmonary fibrosis; Lung neoplasms; Mechanism; Prognosis