Histochemical Studies of Progressive p53 Mutations during Colonic Carcinogenesis in Sprague-Dawley Rats Induced byN-Methyl-N-Nitro-Nitrosoguanidine or Azoxymethane

Yvgeni Tendler,Ron Reshef,Izhak Cohen,Miriam Barzilai,Shaul M. Shasha,Varda Rotter,Tamar Shkolnik

Histochemical Studies of Progressive p53 Mutations during Colonic Carcinogenesis in Sprague-Dawley Rats Induced byN-Methyl-N-Nitro-Nitrosoguanidine or Azoxymethane

1994

Yvgeni Tendler
Ron Reshef
Izhak Cohen
Miriam Barzilai
Shaul M. Shasha
Varda Rotter
Tamar Shkolnik

We studied the increasing expression of the p53 tumor suppressor gene in Sprague-Dawley rats, chemically induced to develop colon cancer. p53 expression was evaluated histochemically at various stages

Keywords:

Immunology
Nitro
Biology
Colorectal cancer
Carcinogenesis
P53 Tumor Suppressor
Tumor progression
Azoxymethane
P53 tumor suppressor gene
Tumor suppressor gene
sprague dawley rats
p53 expression
colon carcinogenesis

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