A Phase III International Randomised Trial Comparing Single with Multiple Fractions for Re-irradiation of Painful Bone Metastases: National Cancer Institute of Canada Clinical Trials Group (NCIC CTG) SC 20

*Toronto e Sunnybrook Regional Cancer Centre, University of Toronto, Ontario, Canada; yMount Vernon Hospital, Mount Vernon Cancer Centre for Cancer Treatment, Northwood, Middlesex, UK; zTom Baker Cancer Centre, University of Calgary, Calgary, Alberta, Canada; xRoyal Adelaide Hospital, North Terrace, Adelaide, Australia; {Instituut Friesland, Borniastraat 36, Leeuwarden, Netherlands; kAdvocate Good Samaritan Cancer Centre, Downers Grove, IL 560515, USA; **Departments of Nutritional Sciences, Laboratory Medicine and Pathology, University of Toronto, Mount Sinai Hospital, Toronto, Ontario, Canada; yyNEIC Clinical Trials Group, Cancer Research Institute, Queens University, Kingston, Ontario, Canada