Optical resolution of 2-methylpiperazine by complex formation with optically active 1-phenyl-1-(o-chlorophenyl)prop-2-yn-1-ol and 1,6-diphenyl-1,6-di(o-chlorophenyl)hexa-2,4-diyne-1,6-diol

An efficient optical resolution of 2-methylpiperazine was achieved by complex formation with the title host compounds. X-Ray crystal structure of a 1:2 complex of (S)-(+)-piperazine and (R)-(−)-1-phenyl-1-(o-chlorophenyl)prop-2-yn-1-ol was studied.