A kinetic and allosteric model for the acetylcholine transporter-vesamicol receptor in synaptic vesicles
1992
The ligand binding relationship between teh acetylcholine transporter (AcChT) and the vesamicol receptor (VR) and the kinetics of active transport were studied in synaptic vesicles purified from the Torpedo electric organ using analogues of AcCh and vesamicol. Methoxyvesamicol, which should exhibit better equilibration properties for kinetics measurements than the more potent parent, inhibits active transport in a nonlinear noncompetitive manner
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
0
References
51
Citations
NaN
KQI