Low-dose prednisolone in early rheumatoid arthritis inhibits collagen type I degradation by matrix metalloproteinases as assessed by serum 1CTP—a possible mechanism for specific inhibition of radiological destruction

Inga-Lill Engvall,Björn Svensson,Annelies Boonen,Désirée van der Heijde,Ulf H. Lerner,Ingiäld Hafström

Low-dose prednisolone in early rheumatoid arthritis inhibits collagen type I degradation by matrix metalloproteinases as assessed by serum 1CTP—a possible mechanism for specific inhibition of radiological destruction

2013

Inga-Lill Engvall
Björn Svensson
Annelies Boonen
Désirée van der Heijde
Ulf H. Lerner
Ingiäld Hafström

OBJECTIVE: To study the effects of low-dose prednisolone on the osteoclast-regulating proteins osteoprotegerin (OPG) and RANK ligand (RANKL) and on markers of bone resorption, 1CTP generated by MMP ...

Keywords:

Inflammation
Prednisolone
Rheumatoid arthritis
RANKL
Bone resorption
Osteoprotegerin
RANK Ligand
Matrix metalloproteinase
Endocrinology
Medicine
Internal medicine

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