Warm paste heating method for dissolving mannitol crystallization

Objective To investigate the feasibility of warm paste heating method in the dissolution of mannitol crystallization.Methods 400 bags of mannitol which crystallized during October 2012 to Apirl 2013 were selected and then were randomly divided into a control group and an experimental group according to the even and odd numbers,200 for each group.The control group used warm-water soak to dissolve mannitol crystallization,while the experimental group used warm paste heating method.The dissolution time of mannitol crystallization,the number of recrystallization during infusion process,and the situation of local pain or phlebitis were observed and compared between the two groups.Results The dissolution time of mannitol crystallization was shorter,the temperature holding time was longer,fewer bags recrystallized during the infusion process,and the incidence of local irritation pain or phlebitis was lower in the experimental group than in the control group,with statistical differences (P ＜ 0.05).Conclusions Warm paste heating method for dissolving mannitol crystallization is simple to operate,convenient,fast,safe,feasible,and effective and has fewer complications.It is worth being clinically generalized. Key words: Warm paste ;  Mannitol ;  Crystallization ;