Abstract 14358: Coronary Anatomy and Comorbidities in Stress-Induced Cardiomyopathy

BACKGROUND: Previous studies indicated patients with stress-induced cardiomyopathy (SIC) present with apical ballooning of the left ventricle during severe emotional stress. The psychosomatic mechanism explaining how emotional stress can cause myocardial dysfunction is hypothesized to be neurogenic coronary vasospasm causing ischemia despite normal coronary anatomy. METHOD: 50 patients (35 F, 15 M) with mean age 62 ±14 years, who were admitted with SIC from 2006 to 2012 were divided into groups by presence or absence of coronary stenosis(CS) for evaluation of coronary anatomy, LV function, risk factor profile, comorbidities, and stress type. RESULTS: 24 patients with mean age of 53 ±2 years without structural CS(Group A) were younger than 26 patients with mean age of 68 ±4 years with minimal, or insignificant CS(Group B): (P:0.015), with CS of LAD (35 ±5%), LCX (45 ±19%), and RCA (50 ±10%):(P:NS). Ejection fraction of 39 ±5 vs. 36 ±4%,Troponin of 9.4 ±2 vs. 6.5 ±6 ng/dl, LDL of 101±15 vs. 78 ±8 mg/dl, HDL...