Realization and characterization of carbonic layers on 4H-SiC for electrochemical detections

Carbon materials are considered building blocks for most of electrochemical sensors. Their biocompatibility allows their use as transducers for biosensors. Furthermore, they can be patterned, giving interest in all-inclusive bioelectrochemical detection devices. In particular, graphene, boron doped diamond, and pyrolyzed photoresist films are suitable for this kind of application, which would give the ability to use these working electrodes within a fully designed apparatus completed by counter and reference electrode. In this paper, a pioneer work is exposed on the synthesis of these materials for use as electrochemical sensors and as transducers for biodetection of acetylcholine by adsorption of acetylthiocholinesterase. The lowest limit of detection reaches 6.98 μM, sensitivity 5.91 μA/mM, and a linear range from 6.98 μM to 0.55 mM.