Cancer Risk Evaluation: Methods and Trends

Preface Introduction MODELS AND APPROACHES Models of cancer development: genetic and environmental influences (Jandrig) Endogenous DNA damage and its relevance for the initiation of carcinogenesis (Epe, Fusser) The IARC Monographs Programme: cancer-hazard identification as a first step in cancer-risk assessment and cancer prevention (Baan, Cogliano) EPIDEMIOLOGICAL RESEARCH The role of epidemiology in cancer risk assessment of non-ionising radiation (Schuz, Berg-Beckhoff, Schlehofer, Blettner) The role of epidemiology in cancer risk assessment of ionizing radiation (Wakeford) ANIMAL STUDIES Animal studies on RF-EMF cancer effects (Dasenbrock, Buschmann) Animal studies in carcinogen identification: The example of power-frequency (50/60 Hz) magnetic fields (McCormick) GENOTOXICITY STUDIES Chromosomal aberrations in human populations and cancer (Obe, Lloyd, Durante) Cytogenetic studies in mammalian somatic cells exposed to radiofrequency radiation: A meta-analysis (Vijayalaxmi , Prihoda) OMICS - A NEW TOOL FOR CANCER RISK ASSESSMENT? Genomics and cancer risk assessment (Schweiger, Timmermann) Transcriptomics and cancer risk assessment (Kemmner) Proteomics and cancer risk assessment (Schramm) CURRENT USE OF OMICS STUDIES FOR CANCER RISK ASSESSMENT Omics in cancer risk assessment: Pathways to disease (Portier, Thomas) What have omics taught us about the health risks associated with exposure to low doses of ionizing radiation? (Morgan, Sowa) Current use of omics studies for cancer risk assessment: Transcriptomics approach in RF-EMF research (Mevissen) Proteomics approach In mobile phone radiation research (Leszczynski) CHALLENGES FOR RISK MANAGEMENT Evaluating the reliability of controversial scientific results (Lerchl) Comparative risk assessment with ionising and non-ionising radiations (Kiefer) Communicating about uncertainties in cancer risk assessment (Wiedemann, Schutz) The Precautionary Principle and radiofrequency exposure from mobile phones (Marchant)