Successful management using combination therapy of endotoxin absorption therapy (PMX) and continuous hemodiafiltration (CVVHDF) of a critically ill burn patient suffering from methicillin-resistant Staphylococcus aureus toxic shock syndrome

Toxic shock syndrome (TSS), which can be life threatening, is defined by clinical and laboratory evidence of fever, skin rash, desquamation, hypotension, and multiple organ failure (MOF) caused by Staphylococcus aureus enterotoxin. Since Frame et al. reported on the first cases of TSS in burned children in 1985, many more have been described [1–8], but reports of cases of TSS in burned adults are very rare [9,10]. This article describes the efficacy of combination therapy of endotoxin absorption therapy (PMX) and continuous hemodiafiltration (CVVHDF) introduced in the early stages of TSS caused by MRSA for the treatment of a critically ill burned adult.