ALDH2 (Aldehyde Dehydrogenase 2) Protects Against Hypoxia-Induced Pulmonary Hypertension

Yu Zhao,Bai-lu Wang,Jian Zhang,Dayu He,Qun Zhang,Chang Pan,Qiuhuan Yuan,Yinan Shi,Haiyang Tang,Feng Xu,Shujian Wei,Yuguo Chen

ALDH2 (Aldehyde Dehydrogenase 2) Protects Against Hypoxia-Induced Pulmonary Hypertension

2019

Yu Zhao
Bai-lu Wang
Jian Zhang
Dayu He
Qun Zhang
Chang Pan
Qiuhuan Yuan
Yinan Shi
Haiyang Tang
Feng Xu
Shujian Wei
Yuguo Chen

Objective: Hypoxia-induced pulmonary hypertension (HPH) increases lipid peroxidation with generation of toxic aldehydes that are metabolized by detoxifying enzymes, including ALDH2 (aldehyde dehydr...

Keywords:

Internal medicine
Biochemistry
Pulmonary hypertension
Diabetes mellitus
Endocrinology
Aldehyde dehydrogenase
ALDH2
Hypoxia (medical)
Biology
Mitochondrial fission
Lipid peroxidation
Pulmonary artery
Pharmacology

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