Comparative Analysis of Pathogenicity, Phylogenetic Relationship and Host Fungal Rice Blast Pathogen Magnaporthe grisea

Magnaporthe grisea is the most devastating pathogen of rice in all over the world and the principal model organism for elucidating the molecular source of fungal disease of plants This study we report the draft sequence of the M grisea genome Examination of the gene set facilitates an insight into the adaptations essential by a fungus to source disease The genome encodes a huge and varied set of secreted proteins with those defined by remarkable carbohydrate binding domains This fungus also possesses a prolonged family of G protein coupled receptors numerous novel virulence associated genes and huge suites of enzymes occupied in secondary metabolism Consistent with a function in fungal pathogenesis the expression of a number of these genes up regulated during the early stages of infection related development The M grisea genome has been subject to invasion and proliferation of active transposable elements reflecting the colonel nature of this fungus imposed by widespread rice cultivation The study will be helpful to describe phylogenetic relations pathogenicity and genome analysis drug design against diseases caused by fungi and cDNA synthesis and amplification to desired targets