Effect of Short-term Treatment with Perindopril, Torsemide and Restricted-sodium Diet in Dogs with Atrioventricular Valvular Insufficiency

Abstract Caro-Vadillo, A., Ynaraja-Ramirez, E. and Montoya-Alonso, J.A. 2006. Effect of short-term treatment with perindopril, torsemide and restricted-sodium diet in dogs with atrioventricular valvular insufficiency. J. Appl. Anim. Res., 29: 105–108. To evaluate the effects of perindopril, torsemide and a low-sodium diet on clinical response in dogs with moderate congestive heart failure, forty-six dogs with moderate congestive heart failure (International Small Animal Cardiac Health stage II) due to mitral valve disease were taken. During 4 weeks all the patients received 0.2 mg/kg perindopril (Coversyl, Servier) SID, 0.2 mg/kg torsemide (Sutril, Novag) SID and a moderate-sodium diet (k/d, Hill's). The treatment was safe, effective and well-tolerated and no major side-effects were observed. There were no significant changes in measured haematological and biochemical variables, including serum electrolyte concentrations and urinary fractional excretion of electrolytes. At the end of the study, all the pa...