Advanced Capabilities of the Multimodal Adaptive Optics Imager
2011
We recently developed several versions of a multimodal adaptive optics (AO) retinal imager, which includes highresolution
scanning laser ophthalmoscopy (SLO) and Fourier domain optical coherence tomography (FDOCT) imaging
channels as well as an auxiliary wide-field line scanning ophthalmoscope (LSO). Some versions have also been
equipped with a fluorescence channel and a retinal tracker. We describe the performance of three key features of the
multimodal AO system including: simultaneous SLO/OCT imaging, which allows SLO/OCT co-registration; a small
animal imaging port, which adjusts the beam diameter at the pupil from 7.5 to 2.5 mm for use with small animals
ubiquitous in biological research or for extended depth-of-focus imaging in humans; and slow scan Doppler flowmetry
imaging using the wide field auxiliary LSO imaging channel. The systems are currently deployed in several
ophthalmology clinics and research laboratories and several investigations have commenced on patients with a variety
of retinal diseases and animals in vision research.
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