Synthesis and Biological Evaluation of Amino Analogues of Ludartin: Potent and Selective Cytotoxic Agents.

Shabir H. Lone,Khursheed A. Bhat,Shakeel‐u‐Rehman Shakeel‐u‐Rehman,Rabiya Majeed,Abid Hamid,Mohd A. Khuroo

Synthesis and Biological Evaluation of Amino Analogues of Ludartin: Potent and Selective Cytotoxic Agents.

2014

Shabir H. Lone
Khursheed A. Bhat
Shakeel‐u‐Rehman Shakeel‐u‐Rehman
Rabiya Majeed
Abid Hamid
Mohd A. Khuroo

Various amino-analogues of the cytotoxic guaianolide ludartin are synthesized by Michael type addition of amines at the highly active α-methylene-γ-lactone motif.

Keywords:

Combinatorial chemistry
Cytotoxic T cell
Cytotoxicity
Terpene
Chemistry
Organic chemistry
biological evaluation

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations