PS1 - 3. The relationship between plasma and brain glucose levels under hypoglycemic conditions in humans

Since glucose is the main source of energy for the brain, understanding the kinetics of brain glucose uptake under hypoglycemic conditions is highly important. Under normo- and hyperglycemic conditions the relationship between plasma and brain glucose levels is linear and behaves according to reversible Michaelis-Menten (MM) kinetics. In the present study brain glucose levels during hypoglycemia were measured by 13C magnetic resonance spectroscopy (MRS).