SINGLE LESION LEPROSY PACIENTS MULTICENTRIC COHORT TREATED WITH SINGLE DOSE DRUG THERAPY: FINDINGS ON THREE-YEAR FOLLOW-UP AND PUBLIC HEALTH PERSPECTIVE IN B RAZIL Coorte multicêntrica de pacientes com hanseníase tratada com terapia de dose única: resultados de três anos de seguimento e perspectiva em sáude pública no Brasil

Single skin lesion, paucibacillary (SSL-PB) leprosy is considered an early disease manifestation. This study evaluated the clinical outcome of a cohort of 259 newly diagnosed SSL-PB treated with one dose of rifampicin, ofloxacin, minocycline (ROM) and followed-up for three-years. Patients were recruited from the North, Central West and Southeast regions in Brazil (1997-2001). The result expected with ROM therapy was disappearance or the reduction of lesion size. Manifestations that required additional