Hardware-assisted High-performance DNA Alignment System.

The investigations of DNA become more and more important in this era. A plethora of new algorithms that were published over the last decade are apparent evidences for this fact. In the DNA's researches, alignment is one of the most important steps that is especially taken care and continuously developed. Despite they already have a lot of algorithms for this problem, and some of them provide impressive enhancements. But it is still far more to state that DNA alignment has already achieved the ideal performance. Therefore, in this work, we promote an efficient architecture which is based on our improved BWA-MEM algorithm that we have already published in [14]. Beside that, we also propose a communication protocol as well as as its API in order to ensure the accuracy and stability of the system. The system offers a speed-up by 18.14x when compared with modern computing platforms.