Renal Cell Carcinoma Clinical Presentation and Histopathological Findings: A Retrospective Analysis of a Jordanian Population at King Hussein Medical Center

Objective: To assess renal cell carcinoma cases and analyze the tumor characteristics in terms of clinical presentation, patient’s demographics and the histopathological findings. Methods: This retrospective study included 99 patients with renal masses, of both sexes and different age groups, who presented at our urology department at Prince Hussein Center for Urology and Organ Transplant with various clinical presentations. Patients were scheduled for nephrectomies during the period of January 1 st 2011 to April 1 st 2013. Demographic data were retrieved and reviewed with the histopathological reports obtained from the histopathology department at Prince Iman laboratory research center. Results: Our patients ranged in age from 27 to 80 years old with male : female incidence ratio of 1.75:1(p<0.05). Renal mass was incidentally discovered in 43.4% of cases (p<0.05). Radical nephrectomy was performed in 90.9% of cases. Clear cell renal cell carcinoma was diagnosed in 71.7% of patients (p<0.05). Conclusion: Clear renal cell carcinoma subtype grade II is the most frequent type of renal cell carcinoma in our Jordanian population. Renal cell carcinoma occurs commonly in males, with no metastases in females and with 6.3% metastases in males.