Affinity separation matrix for Fab region-containing peptide

The present invention aims to provide a manufacturing method of the Fab region-containing peptide used affinity separation matrix is ​​better retention performance and binding capacity for Fab region-containing peptide IgG, and the affinity separation matrix. Affinity separation matrix according to the present invention is characterized in that the Fab region binding peptide is immobilized as a ligand on a water-insoluble carrier at a density of more than 1.0mg / mL-gel.