Correlation between saccadic parameter variations and clinical evidences in thyroid autoimmune ophthalmopathy (TAO) affected patients

Purpose: Object of our study is to value correlation between saccadic parameters, estimated through EOMG exam, and several clinical symptoms/signs in subjects affected by TAO. Methods: 80 eyes of 40 patients consecutive affected by TAO were examinated. All the patients were submitted to ocular motility exam, Hertel's exophthalmometry, clinical evaluation and saccadic movement analisys through Electroculomyography (EOMG; BM6000MOE system - WinEOMG software ). CAS score was calculated in each subject. Results: Most of observed patients showed at least a grade mild exophthalmos. In 40% of observed patients we found an increase of saccadic movement maximal speed; in 30% we found a decrease of movement medium speed. 25% of observed patients showed an increased latency. Almost all subjects with any saccadic alteration, showed exophthalmos. Conclusions: In TAO affected patients seem not to be correlation between CAS score and saccadic alterations or exophthalmos entity. On the contrary, there seem to be a correlation between saccadic alterations and exophthalmos. Even if these data still need to be confirmed, analysis with EOMG could bring an ocular motility alteration predictive value.